Analysis on the time-space dynamic mode of inbound tourists is a core question of geography spatial research on tourist flow. According to the relevant data of inbound tourism in Guangdong during 2000-2009, the author analyses the inter-annual variation, time distribution, dynamical degree, spatial concentration and spatial pattern evolution of inbound tourists in Guangdong province from space scale and time series this two aspects. In the time series, we discuss the temporal dynamic variation of inbound tourists in Guangdong from the inter-annual variation of inbound tourists' occupancy and the year border concentration index of inbound tourists' temporal distribution this two aspects. In the space scale, we study the spatial dynamic variation of inbound tourists in Guangdong from three aspects: the quantity change features of inbound tourists, the spatial centralization index of inbound tourists and the Spatial distribution pattern of inbound tourists. Results show that: 1) in addition to the individual cities, the inter-annual variation of inbound tourists' occupancy in most cities remains stable, the year border concentration index is low and time distribution is uniform; 2)the spatial distribution of inbound tourists in regional differences shows obvious concentration pattern, inbound tourists are mainly concentrated in the pearl river delta region, and a further to this concentration trend; 3) the spatial distribution of inbound tourists in cities' differences emerges from "Center FuSheShi dual-core structure" to "Center FuSheShi multi-core structure"; 4)the spatial distribution pattern of inbound tourists and economic space pattern are basically the same, this presents that the economic development's level and external economic exchanges intensity is the main factors in influencing the spatial distribution of inbound tourists.